منابع مشابه
The prognosis in aplastic anemia.
The biphasic shape of the survival curve of 99 patients with aplastic anemia suggested that there may be at least two subgroups of patients with this disease, one with a very short survival and another with a longer survival. Patients who survived for 4 mo or less after the first clinic visit (group A) were different from the patients who survived longer (group B) with respect to their modes of...
متن کاملPROGNOSIS IN APLASTIC ANEMIA 519 RESULTS Survival
The biphasic shape of the survival curve of 99 patients with aplastic anemia suggested that there may be at least two subgroups of patients with this disease, one with a very short survival and another with a longer survival. Patients who survived for 4 me or less after the first clinic visit (group A) were different from the patients who survived longer (group B) with respect to their modes of...
متن کاملALLOGENIC BONE MARROW TRANSPLANTATION IN APLASTIC ANEMIA
Eighteen patients, twelve men and six women, with aplastic anemia underwent allogenic bone marrow transplantation (BMT) from HLA-matched siblings during the period of 1990 to 1996. The conditioning regimen was cyclophosphamide with or without busulfan, depending on the cause of aplasia. Antilymphocyte globulin (ALG) and cyclosporine were used for rejection and acute GVHD prophylaxis, respe...
متن کاملAplastic Anemia in Children — Prognosis and Survival Rate
Aplastic anemia is a rare disease affecting 1—2 people per one million of the population. The hallmark of the disease is peripheral pancytopenia with hypo cellular bone marrow in the absence of infiltrative disease to the bone marrow. It is classified into moderate, severe, and very severe aplastic anemia based on actual cell count. Damage to the stem cells in the bone marrow is central to the ...
متن کاملAplastic anemia.
PURPOSE OF REVIEW Most acquired aplastic anemia is the result of immune-mediated destruction of hematopoietic stem cells causing pancytopenia and an empty bone marrow, which can be successfully treated with either immunosuppressive therapy or hematopoietic stem-cell transplantation. RECENT FINDINGS In aplastic anemia, oligoclonally expanded cytotoxic T cells induce apoptosis of hematopoietic ...
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ژورنال
عنوان ژورنال: Blood
سال: 1975
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v45.4.517.517